Glimepiride (Glimepiride)
Overview of Glimepiride
Glimepiride is oral hypoglycemic agent. It belongs to sulfonylurea class. Glimepiride is chemically identidied as 1-p-2-(3-ethyl-4-methyl-2-oxo-3 pyrroline-1-carboxamido) ethyl-phenylsulfonyl-3-(trans-4-methylcyclohexyl) urea. It was approved by the Food and Drug Administration in 1995 as an adjunct to diet and exercise to lower the blood glucose in patients with type 2 diabetes whose hyperglycemia cannot be controlled by diet and exercise alone.
Indication of Glimepiride
Glimepiride is primarily indicated in conditions like NIDDM.
Contraindication of Glimepiride
Glimepiride is contraindicated in conditions like Diabetic ketoacidosis.
Side Effects of Glimepiride
The severe or irreversible adverse effects of Glimepiride, which give rise to further complications include Thrombocytopenia, Jaundice, Jaundice, Hepatitus, Haumolytic anaemia.,The symptomatic adverse reactions produced by Glimepiride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Anorexia, Diarrhea, Rashes, Urticaria, Epigastric discomfort, Photosensitivity, Nausea and vomiting, Edema, Hypoglycemia, Hyponatremia.
Precautions of Glimepiride
Glimepiride should be used with caution in patients with diabetes, kidney disease, liver disease, heart disease or if have any allergy. During times of stress such as fever, infection, injury or surgery, it may be more difficult to control blood sugar, consult the doctor or pharmacist if additional medication may be required. This medication should be used only when clearly needed during pregnancy. Must be taken shortly before meals.