Estradiol (Valerate) (Estradiol (Valerate))
Overview of Estradiol (Valerate)
Estradiol (Valerate) is the most potent naturally occuring ovarian and placental estrogen in mammals. Estradiol (Valerate) is has also been produced semi-synthetically. iteffective for replacement therapy in women who is deficient of hormone and used to treat symptoms associated with menopause and conditions in which hormone levels are low and to prevent osteoporosis (bone loss). itadminstered intramuscularly.
Indication of Estradiol (Valerate)
Estradiol (Valerate) is primarily indicated in conditions like Estrogen-responsive prostate carcinoma, Menopausal symptoms, Osteoporosis, and can also be given in adjunctive therapy as an alternative drug of choice in Breast cancer.
Contraindication of Estradiol (Valerate)
Estradiol (Valerate) is contraindicated in conditions like Gall stones,Fibroids,Endometriosis,Estrogen-dependent cancer,Undiagnosed vaginal bleeding,Venous thromboembolic disease.
Side Effects of Estradiol (Valerate)
The signs and symptoms that are produced after the acute overdosage of Estradiol (Valerate) include Sudden / Unsual vaginal bleeding, Nausea & vomiting.,The symptomatic adverse reactions produced by Estradiol (Valerate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Skin reactions, Impotence, Weight gain, Nipple tenderness, Edema, Gynecomastia, Breast tenderness, Hypercalcemia, Withdrwal bleeding.
Precautions of Estradiol (Valerate)
Estradiol should be used with caution in patients with medical history, including family medical history, especially breast lumps and cancer, high blood pressure, diabetes, asthma, epilepsy, migraine headaches, liver, heart or kidney disease, depression, toxemia (high blood pressure during pregnancy), jaundice during pregnancy, excessive weight gain and fluid retention during the menstrual cycle or if have uterine fibroid tumors. Before having surgery, tell the doctor about the use of the drug. Do not use this medication during pregnancy or lactation. This medication may cause fetal harm. Cigarette smoking can increase the chance of blood clots while using this medication (especially in women pass the age of 35). Higher strengths are more likely to cause melasma (darkening of skin), sunlight may intensify this darkening, so avoid prolonged sun exposure and sunlamps. Consult the doctor regarding use of sunscreens and protective clothing.