Zolpidem Tartrate (Zolpidem Tartrate)
Overview of Zolpidem Tartrate
Zolpidem (Tartrate) is a non-benzodiazepine sedative-hypnotic for the short-term treatment of insomnia. Although chemically unrelated to other hypnotics such as the benzodiazepines or barbiturates, zolpidem does share some pharmacological actions with these drugs. Unlike the benzodiazepines, zolpidem produces muscle relaxation and anticonvulsant effects only at doses much higher than the hypnotic dose. Zolpidem has a short half-life and no active metabolites. Therefore, a next-day "hangover" effect and CNS depression are less for zolpidem than the barbiturates. Treatment of insomnia with zolpidem should be restricted to a period of 7-10 days. Zolpidem received FDA approval in 1993.
Indication of Zolpidem Tartrate
Zolpidem Tartrate is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.
Contraindication of Zolpidem Tartrate
Zolpidem (Tartrate) is contraindicated in conditions like Myasthenia gravis,Psychosis,Pulmonary insufficiency,Respiratory depression,Sleep apnea syndrome.
Side Effects of Zolpidem Tartrate
The severe or irreversible adverse effects of Zolpidem (Tartrate), which give rise to further complications include Dementia.,The symptomatic adverse reactions produced by Zolpidem (Tartrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Confusion, GI upset, Depression, Tremor.
Precautions of Zolpidem Tartrate
Zolpidem hemitartrate should be used during pregnancy or lactation only if clearly needed. It should be used with caution in patients with any pre-existing kidney disease, liver disease, lungs disease, history of drug dependence or depression, breathing problems or if have any allergy.