Plasma Protein Fraction (Plasma Protein Fraction)
Overview of Plasma Protein Fraction
Plasma Protein Fraction is a sterile solution of selected proteins derived from the blood plasma of adult human donors. It contains protein, of which about 83-90% is albumin and the remainder is a and ß globulins. Plasma Protein Fraction is used as a substitute for plasma in treating non-hemorrhagic shock and as a source of protien for intravenous nutrition.
Indication of Plasma Protein Fraction
Plasma Protein Fraction is primarily indicated in conditions like Hypovolaemia, and can also be given in adjunctive therapy as an alternative drug of choice in Cardiac insufficiency.
Contraindication of Plasma Protein Fraction
Plasma Protein Fraction is contraindicated in conditions like Anaemia,Congestive heart failure,Hypersensitivity to any component of product.
Side Effects of Plasma Protein Fraction
The symptomatic adverse reactions produced by Plasma Protein Fraction are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Urticaria, Hypotension, Flushing, Back pain.
Precautions of Plasma Protein Fraction
Rapid infusion of Plasma Protein Fraction (greater than 10mL/minute) has produced hypotension in patients undergoing surgery or in the preoperative or postoperative period. Blood pressure should be monitored during use and infusion slowed or ceased if sudden hypotension occurs. Plasma Protein Fraction does not provide coagulation factors and therefore does not correct coagulation disorders.