Epirubicin (Epirubicin)
Overview of Epirubicin
Epirubicin is anthracycline antibiotic.It is an anticancerous agent. and has antineoplastic actions similar to doxorubicin. Epirubicin Hcl is effective in the treatment of different cancers to slow or stop the growth of abnormal cells. Epirubicin Hcl is used in combination with different anticancerous drugs to obtain most excellent therapeutic effects and reduce toxicity or unwanted effects.
Indication of Epirubicin
Epirubicin is primarily indicated in conditions like Bladder carcinoma, Breast cancer, Gastric cancer, Lung cancer, Lymphoma, Ovarian cancer.
Contraindication of Epirubicin
Epirubicin is contraindicated in conditions like Hypersensitivity.
Side Effects of Epirubicin
The severe or irreversible adverse effects of Epirubicin, which give rise to further complications include Vomiting, Dehydration, Hypersensitivity, Hives.,Epirubicin produces potentially life-threatening effects which include Cardiotoxicity, Neutropenic sepsis. which are responsible for the discontinuation of Epirubicin therapy.,The signs and symptoms that are produced after the acute overdosage of Epirubicin include Nausea, Vomiting, Cardiotoxicity, Myelotoxicity.,The symptomatic adverse reactions produced by Epirubicin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fatigue, Nausea, Vomiting, Alopecia, Diarrhea, Mucositis, Urticaria, Hair loss, Hot flushes, Lassitude, Local venous flare.
Precautions of Epirubicin
Epirubicin should be used with caution in elderly, toxic effects are more marked because the clearance is reduced. In hepatic disease, dose reduction according to degree of hepatic failure is advised to avoid serious toxicity. It should be administered only under the supervision of a physician experienced in the use of the chemotherapy. The FDA currently recommends that procedures for proper handling and disposal of antineoplastic agents be considered. Epirubicin may cause increase in skin sensitivity towards sunlight. Donot have any vaccinations during its use. Cautions should be taken in allergic patients.