Diphtheria Antitoxin (Diphtheria Antitoxin)
Overview of Diphtheria Antitoxin
Diphtheria Antitoxin is a sterile preparation containing the specific antitoxic globulins that have the power of neutralising the toxin formed by Corynebacterium diphtheriae. Diphtheria Antitoxin is used for passive immunization in suspected cases of diphtheria.
Indication of Diphtheria Antitoxin
Indications
Contraindication of Diphtheria Antitoxin
Diphtheria Antitoxin is contraindicated in conditions like Asthma,Hypersensitivity to the drug.
Side Effects of Diphtheria Antitoxin
The symptomatic adverse reactions produced by Diphtheria Antitoxin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Fever, Itching, Muscle aching, Swelling of face, Swelling of feet.
Precautions of Diphtheria Antitoxin
Before injecting, information should be obtained whenever possible, as to whether previous injection have been received and whether the patient is subject to hypersensitivity disorders. Sensitivity testing should be performed before administration of antitoxin. The patient must be kept under observation after the administration of full dose. Adrenaline injection and resuscitation facilities should be available.It has a potency of not less than 1000 international units per ml when obtained from horse serum and not less than 500 international units /ml when obtained from otha mammals.