Albendazole (Albendazole)
Overview of Albendazole
Albendazole is a broad spectrum antiparasitic agent, developed as a veterinary anthelmintic and was first approved for humun use in 1982. Albendazole is a benzimidazole carbamate. Chemically Albendazole is identified as [5-(propylthio)-1H-benzimidazol-2y] carbamic acid methyl ester. Albendazole is effective against pin worm infection, ascariasis, trichuriasis and infection with both hookworm species. Albendazole is administerd orally.
Indication of Albendazole
Albendazole is primarily indicated in conditions like Ascariasis, Capillariasis, Enterobiasis, Giardiasis, Hook worm infection, Hydatid disease, Lymphatic filariasis, Microsporidiosis, Neurocysticercosis, Opisthorchis, Pin worm infection, Strongyloidiasis, Tapeworm infection, Thread-worm infection.
Contraindication of Albendazole
Albendazole is contraindicated in conditions like Hypersensitivity to the drug.
Side Effects of Albendazole
The severe or irreversible adverse effects of Albendazole, which give rise to further complications include Reversible neutropenia.,The signs and symptoms that are produced after the acute overdosage of Albendazole include Vomiting, Tachycardia, Diarrhea, Respiratory distress.,The symptomatic adverse reactions produced by Albendazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Abdominal pain, Reversible alopecia.
Precautions of Albendazole
Albendazole should be used with extreme caution in hepatic disease, breast-feeding and during pregnancy.