Basiliximab (Basiliximab)
Overview of Basiliximab
Basiliximab is a chimeric murine monoclonal anti-interleukin-2 receptor (CD25) antibody.Basiliximab is used in conjuntion with other immunosuppressant drugs in patients undergoing organ transplantation to prevent graft rejection.
Indication of Basiliximab
Basiliximab is primarily indicated in conditions like Organ transplantation, Prophylaxis of acute graft rejection episodes, Prophylaxis of acute rejection in allogenic renal transplantation.
Contraindication of Basiliximab
Basiliximab is contraindicated in conditions like Hypersensitivity,Pregnancy,Breast feeding.
Side Effects of Basiliximab
The severe or irreversible adverse effects of Basiliximab, which give rise to further complications include Hypertension, Urinary tract infection.,The symptomatic adverse reactions produced by Basiliximab are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Fever, Dyspnea, Constipation, Insomnia, Abdominal pain, Peripheral edema, Pain, Dysuria, Dyspepsia, Weight gain, Tremor, Cough, Rhinitis.
Precautions of Basiliximab
Basiliximab is not recommended for use during pregnancy or lactation. Immunosuppressant drug should not be given, where possible, to patients with acute infection, dosage reduction or withdrawal should be considered if infection develops, until the infection has been controlled. Blood counts and measurement of hemoglobin concentration should be carried out routinely, help to predict the onset of bone marrow depression. It must be handled with great care and avoid contact with skin and eyes and should not be inhaled.