Zuclopenthixol (Zuclopenthixol)
Overview of Zuclopenthixol
Zuclopenthixol is a tranquillizer, similar to chlorpromazine. Zuclopenthixol is used in the treatment of schizophrenia.
Indication of Zuclopenthixol
Zuclopenthixol is primarily indicated in conditions like Dementia, Enhance permeation of SC or IM inj, Labyrinthine disorders, Mania, Prolactinoma, Psychosis, Schizophrenia, Second trimester abortion.
Contraindication of Zuclopenthixol
Zuclopenthixol is contraindicated in conditions like Alcohol dependence,Parkinsonism,Phaeochromocytoma,Coma,CNS depression.
Side Effects of Zuclopenthixol
Zuclopenthixol produces potentially life-threatening effects which include Fever, Neuroleptic Malignant Syndrome, Hypertonicity. which are responsible for the discontinuation of Zuclopenthixol therapy.,The signs and symptoms that are produced after the acute overdosage of Zuclopenthixol include Convulsions, Coma, Hypothermia, Somnolence, Extrapyramidal effects.,The symptomatic adverse reactions produced by Zuclopenthixol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tachycardia, Parkinsonism, Akathisia, Loss of libido, Dystonic reactions, Menstrual irregularity, Orthostatic hypotension, Benign leucopenia, Tardive dyskinesia.
Precautions of Zuclopenthixol
Zuclopenthixol should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertropy. Photosensitization may occur, caution patients to take appropriate measures (e.g. wear protective clothing or sunscreen) against exposure to sunlight or UV light. Discontinue use atleast 48 hr before myelography.