Xipamide (Xipamide)
Overview of Xipamide
Xipamide is a diuretic and antihypertensive agent. Xipamide is a similar to frusemide but slower onset and longer duration of action. Chemically Xipamide is 5-(aminosulfony)-4-chloro-N (2, 6-dimethylphenyl)-2-hydroxybenzamide. Xipamide is used in control of high blood pressure and in the treatment of fluid over load.
Indication of Xipamide
Xipamide is primarily indicated in conditions like Edema, Hypertension, Left ventricular failure, Oedema.
Contraindication of Xipamide
Contraindications
Side Effects of Xipamide
The severe or irreversible adverse effects of Xipamide, which give rise to further complications include Vertigo, Nocturia, Dizziness.,Xipamide produces potentially life-threatening effects which include Hypokalemia. which are responsible for the discontinuation of Xipamide therapy.
Precautions of Xipamide
Xipamide should be used with caution in patients with diabetes, kidney or liver disease or any drug allergy. Caution must be observed when eating large amounts of food high in potassium such as bananas, baked potatoes, raisins, cooked spinach and other foods. Alcoholic beverages may increase the effects of this drug, causing dizziness or lightheadedness, so limit alcohol intake. It should be used with caution while engaging in activities requiring alertness. This drug changes fluid balance, cause dizziness, if change from a lying to a standing position too rapidly, avoid this by sitting up a few minutes before rising. It should be used with caution during pregnancy or lactation.