Warfarin Na (Warfarin Na)
Overview of Warfarin Na
Warfarin (Na) is a synthetic, oral coumarin prothrombopenic anticoagulant agent. Chemically Warfarin (Na) is identified as 3-(a-acetonylbenzyl)-4-hydroxycoumarin sodium. Warfarin (Na) is also the active ingredient in various rodenticides and insecticides. Warfarin is a racemic mixture of roughly equal amounts of two active isomers; the S-form is roughly 5 times as potent as a vitamin K antagonist than the R-form. Clinically, warfarin is used to prevent and treat thromboembolic disease. Some clinicians believe that warfarin, despite its higher associated risk of bleeding, is preferable to aspirin for prevention of stroke in patients with nonvalvular atrial fibrillation. Warfarin is currently being actively studied to determine its role in acute myocardial infarction. Warfarin was originally approved by the FDA in 1954.
Indication of Warfarin Na
Warfarin Na is primarily indicated in conditions like Anticoagulant, Atrial fibrillation, Deep vein thrombosis, Ischaemic heart disease, Myocardial infarction, Prophylaxis after insertion of prosthetic heart valve, Prophylaxis and treatment of venous thrombosis and pulmonary embolism, Prophylaxis of embolisation in rheumatic heart disease and atrial fibrillation, Systemic embolism, Uncomplicated premature labor, Valvular heart disease.
Contraindication of Warfarin Na
Warfarin (Na) is contraindicated in conditions like Hyperthyroidism,Haemorrhage.
Side Effects of Warfarin Na
The severe or irreversible adverse effects of Warfarin (Na), which give rise to further complications include Alopecia, Purple toes.,Warfarin (Na) produces potentially life-threatening effects which include Hemorrhage. which are responsible for the discontinuation of Warfarin (Na) therapy.,The signs and symptoms that are produced after the acute overdosage of Warfarin (Na) include Cerebral hemorrhage, GI hemorrhage.,The symptomatic adverse reactions produced by Warfarin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Fever, Nausea and vomiting.
Precautions of Warfarin Na
Warfarin should be used with caution in patients with ulcers, unusual menstrual periods, diabetes, liver or kidney disease, high blood pressure, arthritis, thyroid problems, all recent infections, if have had recent surgery or of drug and food allergies. Consult the doctor or pharmacist before switching warfarin products. If patient have an illness that causes vomiting, diarrhea or fever for more than a few days, contact the doctor as these problems can change the effect of warfarin. Limit consumption of alcoholic beverages. In the event of an accidental overdose of warfarin, contact the doctor, poison control center or nearest hospital emergency department immediately. Avoid sudden changes in dietary habits, when use warfarin. Avoid ingesting unusual increases or decreases of foods high in Vitamin K (e.g.liver, cauliflower, cabbage, spinach and other green leafy vegetables, green tea, certain vegetables, cheeses and certain vitamin supplements). It is best to avoid strictly vegetarian diets that consist of foods high in vitamin K.While taking warfarin, be extra careful to avoid injuries, because this medication can cause heavy bleeding. Use an electric razor and be careful while brushing teeth. Warfarin should not be used during pregnancy. Use with caution during lactation.