Tranexamic Acid (Tranexamic Acid)
Overview of Tranexamic Acid
Tranexamic Acid is antifibrinolytic agent. Tranexamic Acid is analogue of aminocaproic acid. Chemically Tranexamic Acid is identified as trans-4-(aminomethyl) cyclohexanecarboxylic acid. Tranexamic Acid is effective to reversed the effects of streptokinase or other fibrinolytic activity. It may be used for conditions in which bleeding control is required such as after surgery or injury, recurrent nosebleeds or abnormal vaginal bleeding.
Indication of Tranexamic Acid
Tranexamic Acid is primarily indicated in conditions like Acute spasm and spasm in diagnostic procedures, Angioneurotic edema, Haemophilia, Prevention of bleeding, Subarachnoid haemorrhage, and can also be given in adjunctive therapy as an alternative drug of choice in Epistaxis, GI hemorrhage, Menorrhagia.
Contraindication of Tranexamic Acid
Tranexamic Acid is contraindicated in conditions like Thrombosis,Renal diseases,Color blindness,Hematuria.
Side Effects of Tranexamic Acid
The severe or irreversible adverse effects of Tranexamic Acid, which give rise to further complications include Acute renal failure, Myopathy.,Tranexamic Acid produces potentially life-threatening effects which include Intracranial thrombosis. which are responsible for the discontinuation of Tranexamic Acid therapy.,The symptomatic adverse reactions produced by Tranexamic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Rashes, Purpura.
Precautions of Tranexamic Acid
Dose of tranexamic acid should be reduced in patients of renal (kidney) insufficiency because of accumulation.