Tocainide Hcl (Tocainide Hcl)
Overview of Tocainide Hcl
Tocainide Hcl is investigational anti-arrhythmic agent. Chemically Tocainide Hcl is a 2-amino-N-(2, 6-dimethylphenyl) propanamide. Tocainide Hcl is a homologue of the desethyl metabolite of lidocaine. Tocainide Hcl is resistant to first pass metabolism. its antiarrhythmic action is similar to that of lidocaine.
Indication of Tocainide Hcl
Tocainide Hcl is primarily indicated in conditions like Myocardial infarction, Ventricular arrhythmias.
Contraindication of Tocainide Hcl
Tocainide (HCl) is contraindicated in conditions like Av block of ii &iii degree.
Side Effects of Tocainide Hcl
The severe or irreversible adverse effects of Tocainide (HCl), which give rise to further complications include Lupus erythematosus, Pulmonary fibrosis, Pulmonary edema, Pneumonitis, Interstitial pneumonitis, Fibrosing alveolitis.,Tocainide (HCl) produces potentially life-threatening effects which include Agranulocytosis, Thrombocytopenia, Blood dyscrasias, Aplastic Anemia, Leucopenia, Aggravation of ventricular arrhythmias. which are responsible for the discontinuation of Tocainide (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Tocainide (HCl) include Convulsions, Respiratory depression, Excitation, Cardiovascular disturbances.,The symptomatic adverse reactions produced by Tocainide (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, SweatingX, Convulsions, Visual hallucinations.
Precautions of Tocainide Hcl
Tocainide should be used with caution in patients of liver or kidney diseases because the rate of elimination may be significantly decreased. Correct any potassium deficit because tocainide is ineffective in hypokalemia.