Spectinomycin Hcl (Spectinomycin Hcl)
Overview of Spectinomycin Hcl
Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. Spectinomycin Hcl is structurally related to aminoglycosides. Spectinomycin lacks amino sugar and glycosidic bonds. Spectinomycin has moderate antibacterial activity against many gram positive and gram negative bacteria but Spectinomycin Hcl is especially effective against Niesseria gonorrhoeae. Antibiotics require constant drug level in body for therapeutic effect. This is achieveD by taking the medication at regular intervals of time throughout the day and night as prescribed. Spectinomycin Hcl is important to take the drug for the full time period as prescribed, discontinuation of the therapy may result in ineffective treatment.
Indication of Spectinomycin Hcl
Spectinomycin Hcl is primarily indicated in conditions like Cervicitits, Gonorrhoea, Proctitis, Urethritis.
Contraindication of Spectinomycin Hcl
Spectinomycin (HCl) is contraindicated in conditions like Pharyngeal gonorrhoea,Complicated gonococcal infection.
Side Effects of Spectinomycin Hcl
Spectinomycin (HCl) produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Spectinomycin (HCl) therapy.,The symptomatic adverse reactions produced by Spectinomycin (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Fever, Chills, Urticaria.
Precautions of Spectinomycin Hcl
Patients receiving spectinomycin for gonorrhea should be tested for syphilis at the time of treatment and 3 months later because the symptoms of syphilis may be masked or delayed by treatment with spectinomycin. Spectinomycin should be used with caution during pregnancy and in the breast feeding mother. Spectinomycin should be used with caution in children because safe use has not been fully established. Spectinomycin reconstituted with bacteriostatic water containing benzyl alcohol should not be administered to neonates. CNS toxicity in neonates and infants has been blamed on inadvertent administration of benzyl alcohol.