Benzylpenicillin (Benzylpenicillin )
Overview of Benzylpenicillin
Benzylpenicillin (Na or K) is a BETA-LACTUM antibiotic and has a bactericidal action against gram-poisitve bacteria, gram-negative cocci, some other gram-negative bacteria, spirochetes, and actinomycetes. It exerts its killing action on growing and dividing bacteria by inhibiting bacterial cell wall synthesis.Benzylpenicillin (Na or K) is used in treatment of a variety of infections including abscess, actinomycosis, anthrax, bites and stings, diptheria etc.
Indication of Benzylpenicillin
Benzylpenicillin is primarily indicated in conditions like Bacterial endocarditis, Bacterial infections, Meningococcal disease, Muscle relaxation, Muscle relaxation for surgery or intubation, Penicillin sensitive infections.
Contraindication of Benzylpenicillin
No data regarding the contra indications of Benzylpenicillin (Na or K) is available.
Side Effects of Benzylpenicillin
The severe or irreversible adverse effects of Benzylpenicillin (Na or K), which give rise to further complications include Convulsions, Renal damage, Hemolytic anemia, Hypersensitivity reactions, Bone marrow hypoplasia, Jarisch herxheimer reaction, Cation intoxication.,Benzylpenicillin (Na or K) produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Benzylpenicillin (Na or K) therapy.,The symptomatic adverse reactions produced by Benzylpenicillin (Na or K) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin rash, Local reactions.
Precautions of Benzylpenicillin
Benzylpenicillin should be used with caution in patients with history of allergy, especially to drugs and in patient hypersensitive to penicillin. Care is necessary if very high dose of penicillin is given, especially if renal (kidney) function is poor. Renal and hematological status should be monitored during prolonged and high dose therapy.