Silver Sulphadiazine (Silver Sulphadiazine)
Overview of Silver Sulphadiazine
Silver Sulphadiazine is a topical anti-infective agent with the antibacterial properties of both silver ion and sulfadiazine. Both free silver and the sulfonamide moiety may exert activity, Silver Sulphadiazine is used to prevent and treat infections of wounds caused by second- and third-degree burns. The drug does not inhibit folic acid synthesis as other sulfonamides do, rather disrupts bacteria by damaging the cell membrane and the cell wall. It has a wide spectrum of bactericidal activity against both gram-positive and gram-negative organisms.
Indication of Silver Sulphadiazine
Silver Sulphadiazine is primarily indicated in conditions like Bacterial infections, Burns and scalds, Infections, Wounds.
Contraindication of Silver Sulphadiazine
Silver Sulphadiazine is contraindicated in conditions like Pregnancy,Hypersensitivity to any component of product.
Side Effects of Silver Sulphadiazine
The severe or irreversible adverse effects of Silver Sulphadiazine, which give rise to further complications include Nephrotic syndrome, Leucopenia, Glomerulonephritis.,The symptomatic adverse reactions produced by Silver Sulphadiazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin rashes.
Precautions of Silver Sulphadiazine
Use silver sulfadiazine with caution in patients with any allergic reaction to any "sulfa" drug and if have liver or kidney disease. Use silver sulfadiazine with caution during pregnancy.