Benztropine (Mesylate) (Benztropine (Mesylate))
Overview of Benztropine (Mesylate)
Benztropine (Mesylate) is a synthetic compound combining the active moieties of atropine and diphenylhydramine. It has anticholinergic, antihistaminic and local anesthetic effects. Benztropine (Mesylate) is antimuscarinic drug of potency one quater that of atropine sulphate and an antihistaminic of potency equal to that of pyrilamine maleate. It also has an antispasmodic properties. Benztropine (Mesylate) is used as an antidyskinetic in the treatment of parkinsonism and for the control of extrapyramidal reactions. Administered orally, intramuscularly and intravenously.
Indication of Benztropine (Mesylate)
Indications
Contraindication of Benztropine (Mesylate)
Benztropine (Mesylate) is contraindicated in conditions like Glucoma,Prostatic hypertrophy.
Side Effects of Benztropine (Mesylate)
The severe or irreversible adverse effects of Benztropine (Mesylate), which give rise to further complications include Blindness, Paralytic ileus.,Benztropine (Mesylate) produces potentially life-threatening effects which include Paralytic ileus. which are responsible for the discontinuation of Benztropine (Mesylate) therapy.,The signs and symptoms that are produced after the acute overdosage of Benztropine (Mesylate) include Nausea, Vomiting, Convulsions, Coma, Blurred vision, Dry flushed skin, Palpitations, Pyrexia, Delirium.,The symptomatic adverse reactions produced by Benztropine (Mesylate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dry mouth, Blurred vision, Confusion, Hallucination.
Precautions of Benztropine (Mesylate)
Benztropine should be used with caution in patients with heart, liver, kidney or obstructive gastrointestinal (GI) diseases. Patient should observe caution while driving or performing other tasks requiring alertness because may impair mental or physical abilities. It should be used with caution in hot weather. Reduce dose or discontinue therapy if loss of appetite or weight occur.