Benzathine Penicillin (Benzathine Penicillin)
Overview of Benzathine Penicillin
Benzathine Penicillin has the same antimicribial activity as benzylpenicillin to which Benzathine Penicillin is hydrolyzed gradually following deep intramuscular injection. its use should be restricted to micro-organisms that are highly susceptible to benzylpenicillin.
Indication of Benzathine Penicillin
Benzathine Penicillin is primarily indicated in conditions like Acute otitis media, Bacterial infections, Diphtheria carriers, Gonorrhoea, Penicillin sensitive infections, Prophylaxis of rheumatic fever, Streptococal impetigo, Syphilis.
Contraindication of Benzathine Penicillin
Benzathine Penicillin is contraindicated in conditions like Seizures.
Side Effects of Benzathine Penicillin
The severe or irreversible adverse effects of Benzathine Penicillin, which give rise to further complications include Urticaria, Allergic reactions, Serum sickness, Skin reactions.,Benzathine Penicillin produces potentially life-threatening effects which include Anaphylactoid reactions. which are responsible for the discontinuation of Benzathine Penicillin therapy.,The symptomatic adverse reactions produced by Benzathine Penicillin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Loose stools, Burning discomfort, Local pain, Deep muscle soreness.
Precautions of Benzathine Penicillin
Benzathine penicillin should be used with caution in patients with medical history especially of any kidney disease, stomach or intestine diseases or allergies to penicillins or other antibiotics. Use with caution during pregnancy or lactation.