Promazine Hcl (Promazine Hcl)
Overview of Promazine Hcl
Promazine Hcl is antipsychotic belongs to phenothiazine. Promazine Hcl is used to treat manifestation of psychotic disorder. Promazine Hcl is effective for the control of nausea and vomiting and for reducing agitation and tension associated with mild alcohol withdrawal.
Indication of Promazine Hcl
Promazine Hcl is primarily indicated in conditions like Adjunct to analgesia, Agitation, Alcohol withdrawal, Insomnia, Intractable hiccup, Muscle spasm of varied aeitology, Psychomotor agitation.
Contraindication of Promazine Hcl
Promazine (HCl) is contraindicated in conditions like Coma,Narrow-angle glaucoma.
Side Effects of Promazine Hcl
The severe or irreversible adverse effects of Promazine (HCl), which give rise to further complications include Parkinsonism, Thrombophlebitis, Extrapyramidal symptoms, Gangrene, Obstructive jaundice, Abnormal liver function, Arteriolar spasm.,Promazine (HCl) produces potentially life-threatening effects which include Agranulocytosis, Leucopenia. which are responsible for the discontinuation of Promazine (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Promazine (HCl) include Coma, Seizures, Hallucinations, Ataxia, Respiratory depression, Grand Mal Seizures (epilepsy), Restlessness, Excitation, Sedation, Rapid fall in BP, CNS excitation, Anxiety, Sleepiness, Deep sleep, Akathisia.,The symptomatic adverse reactions produced by Promazine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Tachycardia, Constipation, Dry mouth, Blurred vision, Confusion, Hypotension, Postural hypotension, Nasal congestion, Urinary hesitancy, Epilepsy, Breast enlargement.
Precautions of Promazine Hcl
Promazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal (kidney) impairment, prostatic hypertropy. Photosensitization may occur, caution patients against exposure to sunlight or UV light. Discontinue use atleast 48 hr before myelography.