Bendrofluazide (Bendrofluazide)
Overview of Bendrofluazide
Bendrofluazide is a diuretic. Bendrofluazide is used in hypertention to lower the high blood pressure. It increases urination and is used to treat fluid overload (abnormal accumulation of fliuid in body cavities, tissue etc). It acts by reducing sodium reabsorption in the kidney. Less potent than frusemide and mersalyl but has longer action. Bendrofluazide is effective orally.
Indication of Bendrofluazide
Bendrofluazide is primarily indicated in conditions like Diabetes insipidus, Disorders of calcium balance, Heart failure, Hypertension, Oedema, Peripheral edema.
Contraindication of Bendrofluazide
Contraindications
Side Effects of Bendrofluazide
The severe or irreversible adverse effects of Bendrofluazide, which give rise to further complications include Thrombocytopenia, Cholestatic jaundice, Aplastic anemia, Hemolytic anemia, Photosensitivity, Necrotizing vasculitis, Acute interstitial pulmonary edema, Skin rashes.,Bendrofluazide produces potentially life-threatening effects which include Hyponatremia, Hypokalemia, Cardiac arrhythmias, Abnormal lipid profile. which are responsible for the discontinuation of Bendrofluazide therapy.,The signs and symptoms that are produced after the acute overdosage of Bendrofluazide include Hypotension, Volume depletion, Hypokalemia, Hyponatremia.,The symptomatic adverse reactions produced by Bendrofluazide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Gout, Impotence.
Precautions of Bendrofluazide
Bendrofluazide should be used with caution in patients with diabetes, kidney or liver disease or any drug allergy. Caution must be observed when eating large amounts of food high in potassium such as bananas, baked potatoes, raisins, cooked spinach and other foods. Alcoholic beverages may increase the effects of this drug, causing dizziness or lightheadedness, so limit alcohol intake. Use caution while engaging in activities requiring alertness. This drug changes fluid balance, cause dizziness, if change from a lying to a standing position too rapidly, avoid this by sitting up a few minutes before rising. It should be used with caution during pregnancy or lactation.