Papaverine Hcl (Papaverine Hcl)
Overview of Papaverine Hcl
Papaverine Hcl is alkaloid devoid of narcotic properties and was first described and extracted from opium in 1848 and later synthesized in 1990. Papaverine Hcl is a hydrochloride salt of opium alkaloid that may be obtained from opium after separation of morphine or prepared synthetically. Chemically Papaverine Hcl is 6, 7-dimethoxy-1-veratrylisoquinoline. Papaverine Hcl is a smooth muscle relaxant, dilates the arteries and increase the blood flow to the obstructed region, especially in the treatment of cerebral and the peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias. Papaverine Hcl is administered orally, intravenously and intramuscularly.
Indication of Papaverine Hcl
Papaverine Hcl is primarily indicated in conditions like Bronchospasm, Cerebral ischaemia, Cerebrovascular disease, Myocardial ischaemia, Pulmonary embolism, Smooth muscle spasm.
Contraindication of Papaverine Hcl
Papaverine (HCl) is contraindicated in conditions like Glucoma,Myocardial infarction,Cardiac failure,Cardiac stroke,Heart block,Bradycardia,Liver diseases.
Side Effects of Papaverine Hcl
The severe or irreversible adverse effects of Papaverine (HCl), which give rise to further complications include Jaundice, Precipitation of glaucoma.,The symptomatic adverse reactions produced by Papaverine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Drowsiness, Blurred vision.
Precautions of Papaverine Hcl
Papaverine should be used wit caution in patients of glaucoma.