Nitrazepam (Nitrazepam)
Overview of Nitrazepam
Nitrazepam is a 1,4-benzodiazipine. A substituent in the 7th position such as halogen or a nitro group is required for its sedative-hypnotic activity. It has depressant action on CNS. Used in the treatment of insomnia. Nitrazepam is not available in any combination preparations.Nitrazepam is administered orally. May cause dependence even in therapeutic dosage.
Indication of Nitrazepam
Nitrazepam is primarily indicated in conditions like Warts.
Contraindication of Nitrazepam
No data regarding the contra indications of Nitrazepam is available.
Side Effects of Nitrazepam
The severe or irreversible adverse effects of Nitrazepam, which give rise to further complications include Aggression, Anxiety, Aggression.,Nitrazepam produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Nitrazepam therapy.,The signs and symptoms that are produced after the acute overdosage of Nitrazepam include Drowsiness, Drowsiness, Ataxia, Sedation, Dysarthria.,The symptomatic adverse reactions produced by Nitrazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Constipation, Blurred vision, VertigoX, Hypotension, Loss of libido, Slurred speech, Respiratory depression, Hypotension.
Precautions of Nitrazepam
Perform periodic blood counts and liver function tests during long term therapy. Nitrazepam should be used with caution in patients if increased salivation cause respiratory difficulty, because it may produce an increase in salivation. Give least amount of drug to patients in whom depression accompanies anxiety and suicidal tendencies may be present. It should be used with caution (if it contains tartrazine) in patients with aspirin hypersensitivity because it may cause allergic reaction (including bronchial asthma). It should be used with caution in patients with porphyria.