Netilmicin sulphate (Netilmicin sulphate)
Overview of Netilmicin sulphate
Netilmicin is a semisynthetic aminoglycoside antibiotic derived from sisomicin, having a range of antibacterial activity similar to that of gentamicin and tobramycin. The sulphate salt of netilmicin, administered intramuscularly and intravenously in the treatment of wide variety of infections caused by susceptible gram-negative organism. Netilmicin (Sulphate) is active alone but also exhibit synergism with ß lactam antibiotic. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Netilmicin (Sulphate) is important to take the drug for the full time period as prescribed. Discontinuation of the therapy may result in ineffective treatment.
Indication of Netilmicin sulphate
Netilmicin Sulphate is primarily indicated in conditions like Advanced breast cancer in postmenopausal women, Bacterial infections, Gonorrhoea, Heart failure, Joint infections, Septicaemia, Serious gram -ve infections resistant to gentamicin, Supraventricular arrhythmias (particularly atrial fibrillation), Surgical infections, Urinary tract infection, UTI.
Contraindication of Netilmicin sulphate
No data regarding the contra indications of Netilmicin (Sulphate) is available.
Side Effects of Netilmicin sulphate
The severe or irreversible adverse effects of Netilmicin (Sulphate), which give rise to further complications include Nephrotoxicity, Ototoxicity.,Netilmicin (Sulphate) produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Netilmicin (Sulphate) therapy.,The symptomatic adverse reactions produced by Netilmicin (Sulphate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Maculopapular rash, Urticaria, Pain, Phlebitis, Elevated hepatic transaminases.
Precautions of Netilmicin sulphate
Netlimicin should be used with caution in patients with history of kidney diseases, vertigo, hearing loss, myasthenia gravis, parkinsonisms. It should be used with caution in patients who are sensitive to aminoglycosides. Keep patients well hydrated to prevent chemical irritation or nephrotoxic reactions. Take appropriate measures in case of secondary infections.