Azlocillin Na (Azlocillin Na)
Overview of Azlocillin Na
Almost 70 years ago, Alexander Fleming reported his discovery of penicillin in 1929. Chain, Flory and their associates succeeded in producing significant quantities of the first penicillins from the cultures of Penicillium notatum in 1940. Ten years later virtually unlimited quantities of penicillin G were available for clinical use. Azlocillin is a broad spectrum penicillin antibiotic. Penicillin is derived directly or indirectly from strains of fungi of the genus Penicillium and other soil inhibiting fungi grown on special culture media. Penicillins are active against most bacterias especially gram positive pathogens (streptococci, staphylococci, pneumococci), some negative strains (gonococci, meningoccocci), some spirochetes and some fugi. The structure of penicillin consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain.
Indication of Azlocillin Na
Azlocillin Na is primarily indicated in conditions like Infection in immunocompromised patients, Meningitis, Urinary tract infection.
Contraindication of Azlocillin Na
Azlocillin (Na) is contraindicated in conditions like Cardiac insufficiency,Hypersensitivity,Hemorrhagic diathesis.
Side Effects of Azlocillin Na
The severe or irreversible adverse effects of Azlocillin (Na), which give rise to further complications include Hypokalemia.,The signs and symptoms that are produced after the acute overdosage of Azlocillin (Na) include Renal insufficiency, Neurotoxicity, Epileptic seizures.,The symptomatic adverse reactions produced by Azlocillin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Phlebitis.
Precautions of Azlocillin Na
It should be used with caution in patients in whom sodium overload could lead to cardiac insufficiency and in patients with renal dysfunction. Use of azlocilline should be avoided during first trimester of pregnancy.