Mefloquine Hcl (Mefloquine Hcl)
Overview of Mefloquine Hcl
Mefloquine Hcl is antimalarial effective in the treatment and prevention of infections resistant to Chloroquine and other antimalarials.Mefloquine Hcl is a synthetic 4-quinoline methanol derivative, chemically related to quinine. Mefloquine Hcl is effective against Plasmodium vivax, Plasmodium ovale, Plasmodium malariae and multidrug resistant falciparum malaria. Mefloquine Hcl is administered orally. May increase the risk of convulsion in epileptic patients. Also a risk of fatal arrhythmias if given together with Halofantrine.
Indication of Mefloquine Hcl
Mefloquine Hcl is primarily indicated in conditions like Adjunctive therapy without valproate, Malaria caused by plasmodium falciparum, Malaria caused by plasmodium vivax, Malaria prophylaxis, To reduce degradation of pancreatic enzyme supplements, Uncomplicated malaria.
Contraindication of Mefloquine Hcl
Mefloquine (HCl) is contraindicated in conditions like Epilepsy,Psychiatric disease,Hypersensitivity.
Side Effects of Mefloquine Hcl
The severe or irreversible adverse effects of Mefloquine (HCl), which give rise to further complications include Convulsions, Hallucinations, Hallucinations, Stevens johnson syndrome, Stevens johnson syndrome, Leucopenia, Seizures, Behavioral disorders.,Mefloquine (HCl) produces potentially life-threatening effects which include Aplastic Anemia, Exfoliative dermatitis, Aplastic anemia, Cutaneous vasculitis. which are responsible for the discontinuation of Mefloquine (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Mefloquine (HCl) include GI disturbances, Psychosis.,The symptomatic adverse reactions produced by Mefloquine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Anorexia, Diarrhea, Constipation, Urticaria, Pruritus, VertigoX, Asthenia, Arthralgia, Hair loss, Sinus bradycardia, Stomachache, Hearing disturbances, Pulse irregularities, Sialorrhea, Visual disturbances, dizziness.
Precautions of Mefloquine Hcl
Mefloquine should be used with caution in patients with any psychiatric disorders, heart problems, seizure disorders and any allergy, especially allergy to other drugs. It should be used with caution in children. It should be used only when clearly needed during pregnancy or lactation.