Detail Drug Information

Maprotiline Hcl (Maprotiline Hcl)

Overview of Maprotiline Hcl

Maprotiline Hcl is antidepressant, with action and uses and adverse effects similar to imipramine. Maprotiline Hcl is administered orally.

Indication of Maprotiline Hcl

Maprotiline Hcl is primarily indicated in conditions like Depression.

Contraindication of Maprotiline Hcl

Maprotiline (HCl) is contraindicated in conditions like Epilepsy,Mania,Myocardial infarction,Urinary retention (adynamic bladder),Narrow-angle glaucoma.

Side Effects of Maprotiline Hcl

The severe or irreversible adverse effects of Maprotiline (HCl), which give rise to further complications include Cholestatic jaundice, Cholestatic jaundice, Grand-mal seizures, Agranulocytosis, Grand-mal seizures.,The signs and symptoms that are produced after the acute overdosage of Maprotiline (HCl) include Coma, Seizures.,The symptomatic adverse reactions produced by Maprotiline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Palpitation, Tremors, Constipation, Skin rashes, Dry mouth, Hypotension, Faintness, Dry mouth, Skin rashes, dizziness, faintness.

Precautions of Maprotiline Hcl

Maprotiline should be used with caution (if it contains tartrazine) in patients with aspirin hypersensitivity, because it may produce allergic reaction (including bronchial asthma). Monitor ECG before initiating large doses. Avoid concurrent administration with electric shock therapy because may increase the hazards of therapy. Perform periodic leukocytes (white blood cells) counts and liver function tests. Photosensitization may occur so caution patients to take protective measures, sunscreen e.t.c, against exposure to UV light or sun light. Following prolong therapy in high doses, abrupt discontinuation of maprotiline should be avoided because it may precipitate the symptoms of the cholinergic rebound such as nausea, vomiting or diarrhea etc. It should be used with extreme caution in case of pre-existing seizures, Parkinsonism, patient with respiratory depression and cardiac diseases. IM injection should be administered with caution in the patient receiving maprotiline. The drug should only be used during pregnancy if clearly needed.