Astemizole (Astemizole)
Overview of Astemizole
Astemizole is an antihistamine. Astemizole is an oral H-1 receptor antagonist that is similar in structure to terfenadine, another H-1 receptor antagonist. It provides relief from symptoms of allergies such as rash, hives, watery eyes, runny nose, itching of eyes and sneezing.
Indication of Astemizole
Astemizole is primarily indicated in conditions like Allergic conjunctivitis, Allergic rhinitis, Asthma, Dermatitis, Urticaria.
Contraindication of Astemizole
Astemizole is contraindicated in conditions like Cardiac insufficiency,Hepatic dysfunction.
Side Effects of Astemizole
Astemizole produces potentially life-threatening effects which include Ventricular fibrillation, Stevens Johnson syndrome. which are responsible for the discontinuation of Astemizole therapy.,The signs and symptoms that are produced after the acute overdosage of Astemizole include Cardiac dysrhythmias.,The symptomatic adverse reactions produced by Astemizole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Nausea, Anxiety, Dry mouth, Pain, Xerostomia.
Precautions of Astemizole
Astemizole should be used with caution in patients with pre-existing heart, kidney or liver disease, asthma or breathing problems, allergy or a history of drug dependance. It is classified as pregnancy category C. This drug should be used only if clearly needed during pregnancy or lactation.