Glucose (Glucose)
Overview of Glucose
Glucose is aldohexose also known as dextrose, occuring as the D-form and found as a free monosaccharide in fruits and other plants and in the normal blood of all animals. Glucose is the chief source of energy for living organisms, its utilization is being controlled by insulin.
Indication of Glucose
Glucose is primarily indicated in conditions like Carbohydrate depletion, Dehydration, Energy source, Fluid depletion, Hypoglycaemia, Water replacement, and can also be given in adjunctive therapy as an alternative drug of choice in Cerebral oedema, Varicose veins.
Contraindication of Glucose
Glucose is contraindicated in conditions like Diabetes mellitus,Anuria,Thiamine deficiency,Trauma,Intracranial hemorrhage,Sepsis,Hypophosphataemia,Haemodilution,Acute ischaemic stroke.
Side Effects of Glucose
The severe or irreversible adverse effects of Glucose, which give rise to further complications include Anaphylactoid reactions, Seizures, Water intoxication, Diabetes mellitus.,Glucose produces potentially life-threatening effects which include Coma, Heart failure, Edema, Sodium retention. which are responsible for the discontinuation of Glucose therapy.,The symptomatic adverse reactions produced by Glucose are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thrombophlebitis, Hypokalemia, Hypomagnesemia, Paresthesias, Hypophosphatemia, Vein irritation, Pain at injection site.
Precautions of Glucose
Perform clinical evaluations and laboratory determination to monitor fluid balance, electrolytes concentration and acid-base balance. There may be the chances of hyperglycemia and glycosuria in such conditions slow the infusion rate monitor blood or urine glucose, if necessary administered insulin. When concentrated glucose infusion is abruptly withdrawn, administered 5% or 10% glucose.