Ergotamine Tartrate (Ergotamine Tartrate)
Overview of Ergotamine Tartrate
Ergotamine (Tartrate) is alkaloid derived from ergot, consisting of lysergic acis, ammonia, proline, phenylalanine and pyruvic acid combined in amide linkages. Ergotamine (Tartrate) is used as an analgesic in the treatment of migraine and cluster headaches.
Indication of Ergotamine Tartrate
Ergotamine Tartrate is primarily indicated in conditions like Migraine, Prophylactic treatment of vascular headache, Vascular headaches.
Contraindication of Ergotamine Tartrate
Ergotamine (Tartrate) is contraindicated in conditions like Hypertension,Renal diseases,Hepatic disease,Chronic pulmonary disease,Vascular disease,Collagen disease,Cachexia,Valvular heart disease.
Side Effects of Ergotamine Tartrate
The severe or irreversible adverse effects of Ergotamine (Tartrate), which give rise to further complications include Ventricular fibrillation, Retroperitoneal fibrosis, Pleuropulmonary fibrosis, Endocardial fibrosis, Cerebral hemorrhage, Stroke.,Ergotamine (Tartrate) produces potentially life-threatening effects which include Myocardial infarction, Renal failure, Vascular occlusions, Necrosis of bowel, Gangrene of extremities. which are responsible for the discontinuation of Ergotamine (Tartrate) therapy.,The signs and symptoms that are produced after the acute overdosage of Ergotamine (Tartrate) include Nausea, Vomiting, Tachycardia, Diarrhea, Coma, Extreme Thirst, Confusion, Pallor, Cold extremities, Tingling.,The symptomatic adverse reactions produced by Ergotamine (Tartrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Nausea, Vomiting, Abdominal pain, Numbness, Cyanosis, Muscle pain, Oedema, Poresthesia.
Precautions of Ergotamine Tartrate
Avoid prolong administration or excessive dosage of ergotamine because of danger of gangrene, ergotism and patients become dependent upon it. It is Contraindicated in Pregnancy Risk of renal Vasoconstriction Avoid in liver impairment