Enflurane (Enflurane)
Overview of Enflurane
Enflurane is inhalation anesthetic. Inhaled gases are the mainstay of anesthesia and are primarily used for the maintenance of anesthesia after administration of an intravenous agent. The depth of anesthesia can be rapidly altered by changing the concentration of inhaled anesthetic. Most of the agents are rapidly eliminated from the body and donot cause post-operative respirtory depression.
Indication of Enflurane
Enflurane is primarily indicated in conditions like Induction and maintenance of anaesthesia, Reactive airways disease, and can also be given in adjunctive therapy as an alternative drug of choice in Obstetric anaesthesia, Obstetric pain.
Contraindication of Enflurane
Contraindications
Side Effects of Enflurane
The severe or irreversible adverse effects of Enflurane, which give rise to further complications include Bronchospasm, Bronchospasm, Asthmatic attack.,Enflurane produces potentially life-threatening effects which include Malignant hyperpyrexia. which are responsible for the discontinuation of Enflurane therapy.,The signs and symptoms that are produced after the acute overdosage of Enflurane include Depression of vital functions.,The symptomatic adverse reactions produced by Enflurane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Hypotension, Respiratory depression, Shivering, Hiccough, Arrhythmia.
Precautions of Enflurane
Enflurane should be used with caution in patients with convulsive disorder. Avoid use in patients having susceptibility to malignant hyperthermia. Patients should observed caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Patients with chronic disease such as diabetes or hypertension may require adjustment to their therapy before anesthesia. Anesthetics should be given with caution in patients with cardiac, respiratory, renal or hepatic impairment. It should be used with caution in elderly patients because they often have significantly decreased MACs and are more susceptible to anesthetic-induced hypotension and circulatory depression. It is classified as category B drug, it should be used with caution during pregnancy.