Doxapram (Doxapram)
Overview of Doxapram
Doxapram Hcl is a central nervous system stimulant and is used to stimulate respiration in post-anesthesia, chronic pulmonary disease etc. Administered intravenously.
Indication of Doxapram
Doxapram is primarily indicated in conditions like Lung damage, Lung infection, Respiratory depression, Respiratory failure, and can also be given in adjunctive therapy as an alternative drug of choice in Neonatal apnea.
Contraindication of Doxapram
Doxapram is contraindicated in conditions like Cerebral oedema,Epilepsy,Hypertension,Hyperthyroidism,Phaeochromocytoma,Convulsions,Obstructive airway disease,Heart disease,Cerebrovascular accident,Coronary artery disease,Hypersensitivity,Neonates.
Side Effects of Doxapram
The severe or irreversible adverse effects of Doxapram, which give rise to further complications include Fever, Allergic reactions, Hepatic necrosis, Seizures, Hypertension, Chest pain, Irregular heart beat.,Doxapram produces potentially life-threatening effects which include Respiratory Failure, Respiratory failure, Hypoxemia, Hypoxemia. which are responsible for the discontinuation of Doxapram therapy.,The signs and symptoms that are produced after the acute overdosage of Doxapram include Tachycardia, Confusion, Sweating, Agitation, Hypertension, Sweating, Fasciculation of skeletal muscles, Cough, Dyspnea.,The symptomatic adverse reactions produced by Doxapram are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Dyspnea, Sweating, Confusion, Itching, Coughing, Cough, Nausea and vomiting, Skin sensitization, Bronchospasm, Laryngospasm, Micturition problems, Hiccups, Confusion, dizziness.
Precautions of Doxapram
Monitor blood pressure continuously. If sudden hypotension or dyspnea develop, discontinue use of doxapram. It should be used with caution in patients with chronic obstructive pulmonary disease. Hepatic and renal impairment.