Dipyridamole (Dipyridamole)
Overview of Dipyridamole
Dipyridamole is 2, 6-Bis (diethanolamino)-4, 8-dipiperidinopyrimido- (5, 4-d) pyrimidine. Dipyridamole is a platelet aggregation inhibitor. It prevents the blood cells from clumping together and keeps the blood flow smooth.
Indication of Dipyridamole
Dipyridamole is primarily indicated in conditions like Ischemic stroke prophylaxis, Secondary prevention of ischaemic stroke and tias, Transient ischemic attacks prophylaxis, and can also be given in adjunctive therapy as an alternative drug of choice in Analgesia and suppression of respiratory activity.
Contraindication of Dipyridamole
Dipyridamole is contraindicated in conditions like Bleeding disorders.
Side Effects of Dipyridamole
The severe or irreversible adverse effects of Dipyridamole, which give rise to further complications include Angina.,Dipyridamole produces potentially life-threatening effects which include Hemorrhage, Coronary steel, Hemorrhage. which are responsible for the discontinuation of Dipyridamole therapy.,The signs and symptoms that are produced after the acute overdosage of Dipyridamole include Flushing.,The symptomatic adverse reactions produced by Dipyridamole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Nausea, Vomiting, Diarrhea, Pruritus, Skin rash, Facial flushing, Syncope, GI disturbance, dizziness, Fainting.
Precautions of Dipyridamole
Dipyridamole should not be used in patients with hypotension unstable angina, aorticstenosis, recent myolar dial infarction because it will produced peripheral vasodilation. It should be used with caution in patient with asthma. It is classified as pregnancy category B and should be used with caution in pregnancy only if clearly needed.