Diclofenac Na (Diclofenac Na)
Overview of Diclofenac Na
Diclofenac (Na) is NSAID (non-steroidal anti-inflammatory drug). Diclofenac (Na) is a simple phenylacetic acid derivative. It resembles both flurbiprofen and meclofenamate. It reduces fever and inflammation and relieves pain.
Indication of Diclofenac Na
Diclofenac Na is primarily indicated in conditions like Acute exacerbation of pain and post operative pain, Acute gout, Ankylosing spondylitis, Bursitis, Gastro-oesophageal reflux disease, Juvenile chronic arthritis, Low back pain, Musculoskeletal disorders, Osteoarthritis, Peptic ulcer, Periarthritis, Pernicious anaemia and other macrocytic anaemias, Post-operative pain, Prevention of postoperative pain, Rheumatoid arthritis, Sprains, Strains, Tendinitis, Tenosynovitis, Tobacco amblyopia and leber's optic atrophy, Ureteric colic.
Contraindication of Diclofenac Na
Diclofenac (Na) is contraindicated in conditions like Asthma,Peptic ulcer,Renal impairment,Hypersensitivity,GI bleeding,Hemorrhagic diathesis.
Side Effects of Diclofenac Na
The severe or irreversible adverse effects of Diclofenac (Na), which give rise to further complications include Anaphylactoid reactions, Nephrotic syndrome, Blood dyscrasias, Peptic ulceration, Bleeding, Lower gut disorders, Papillary necrosis.,Diclofenac (Na) produces potentially life-threatening effects which include Blood dyscrasias, perforation of peptic ulcer, Anaphylaxis, GI hemorrhage. which are responsible for the discontinuation of Diclofenac (Na) therapy.,The signs and symptoms that are produced after the acute overdosage of Diclofenac (Na) include Nausea, Vomiting, Melena, Jaundice, Unconsciousness, Dizziness, Headache, Hepatopathy, Oliguria or anuria, Myoclonic encephalopathy, GI hemorrhage, Somnolence, Upper abdominal pain, Hiccup.,The symptomatic adverse reactions produced by Diclofenac (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Vertigo, Tiredness, Headache, Drowsiness, Irritability, Nausea, Vomiting, Anorexia, Diarrhea, Anxiety, Tremors, Abdominal cramps, Constipation, Insomnia, Rashes, Pain, Itching, Burning, Dyspepsia, Depression, Nightmares, Epigastric pain, Taste disturbances, Eye irritation, Paresthesias, Vision disturbances, Hearing disturbances, ulceration of conjuctiva and cornea,.
Precautions of Diclofenac Na
Diclofenac sodium should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. It should be used with caution in patients with compromised cardiac function, hypertension and other conditions predisposing to fluid retention. It should be used with extra care in the presence of existing uncontrolled infection. Perform periodic auditory (hearing) function test during chronic therapy. Discontinue drug if skin reaction occurs.