Trametinib (Trametinib)
Overview of Trametinib
Trametinib dimethyl sulfoxide is a kinase inhibitor. The chemical name is acetamide, N-[3-[3� 234 cyclopropyl-5-[(2-fluoro-4- iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl- 2,4,7� 235 trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compound with 1,1�-sulfinylbis[methane] (1:1). It is used in the treatment of patients with unresectable or metastatic Melanoma with BRAF V600E or V600K mutations.
Indication of Trametinib
Trametinib is primarily indicated in conditions like Metastatic melanoma, Metastatic melanoma.
Contraindication of Trametinib
No data regarding the contra indications of Trametinib is available.
Side Effects of Trametinib
The symptomatic adverse reactions produced by Trametinib are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Rash, lymphedema.
Precautions of Trametinib
cardiomyopathy, Retinal Pigment Epithelial Detachment, retinal Vein Occlusion, Interstitial Lung Disease, Serious Skin Toxicity, Embryofetal toxicity