loteprednol (loteprednol)
Overview of loteprednol
loteprednol (as Loteprednol Etabonate) contains a sterile, topical anti-inflammatory corticosteroid for ophthalmic use. Loteprednol etabonate is a white to off white powder.chemically it is chloromethyl 17a-[(ethoxycarbonyl)oxy]-11ß-hydroxy-3-oxoandrosta-1,4-diene-17ß-carboxylate. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye.
Indication of loteprednol
loteprednol is primarily indicated in conditions like Acne rosacea, Conjunctivitis, Herpes zoster, Iritis, Keratitis, Uveitis.
Contraindication of loteprednol
No data regarding the contra indications of loteprednol is available.
Side Effects of loteprednol
The symptomatic adverse reactions produced by loteprednol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Eye Pain, Foreign body sensation, elevated intraocular presure, posterior subcapsular cataract formation, herpes simplex, anterior chamber inflammation.
Precautions of loteprednol
Intraocular pressure (IOP) increase - Prolonged use of corticosteroids may result in glaucoma with damage to theoptic nerve, defects in visual acuity and fields of vision. If thisproduct is used for 10 days or longer, IOP should be monitored.Cataracts , delay healing after cataract surgery,bacterial infection, viral infection, funcl infection,patients should not wear contact lenes during their course of therapy with loteprednol.