iloperidone (iloperidone)
Overview of iloperidone
iloperidone is an atypical antipsychotic agent indicated for the treatment of schizophrenia in adults. it belongs to the chemical class of piperidinyl-benzisoxazole derivatives. Its chemical name is 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone. Its molecular formula is C24H27FN2O4 and its molecular weight is 426.48. The structural formula is: iloperidone Structural Formula Illustration
Indication of iloperidone
Indications
Contraindication of iloperidone
No data regarding the contra indications of iloperidone is available.
Side Effects of iloperidone
The symptomatic adverse reactions produced by iloperidone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Tachycardia, Dry mouth, Weight gain, Somnolence, Nasal congestion, Orthostatic hypotension, Dry mouth, dizziness, Tachycardia.
Precautions of iloperidone
eldery patient with demntia related phychosis are not approved to treat with iloperidone Abrupt discontinuation is not advised � Cognitive and motor impairment risk � Concomitant use with drugs that prolong the QT interval should be avoided � Diabetes mellitus or risk factors for diabetes mellitus; increased risk of severe hyperglycemia � Dysphagia risk (risk of aspiration) � Exposure to extreme temperatures (hypothermia) � Elderly patients, particularly elderly women, are at increased risk of tardive dyskinesia � Hematological disease (neutropenia, agranulocytosis, etc) � Hepatic disease � Hypotensive medication use, low BP � Increased duration of therapy and/or higher cumulative doses � Seizure disorder, history, or conditions which lower seizure threshold � Substance abuse history � Risk of suicide � Tardive dyskinesia, potentially irreversible