Roflumilast (Roflumilast)
Overview of Roflumilast
Roflumilast is a PDE4 inhibitor, an NSAID for the treatment of COPD. It acts by antagonizing the PDE4.
Indication of Roflumilast
Roflumilast is primarily indicated in conditions like Chronic bronchitis, Chronic obstructive pulmonary disease.
Contraindication of Roflumilast
Roflumilast is contraindicated in conditions like Hepatic impairment,Hypersensitivity.
Side Effects of Roflumilast
Roflumilast produces potentially life-threatening effects which include Suicidal ideation. which are responsible for the discontinuation of Roflumilast therapy.,The signs and symptoms that are produced after the acute overdosage of Roflumilast include Palpitations, Dizziness, Headache, GI disturbances, aterial hypotension.,The symptomatic adverse reactions produced by Roflumilast are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Diarrhea, Insomnia, Abdominal pain, Decreased appetite, Weight loss.
Precautions of Roflumilast
Not to be use as a rescue medicinal product for acute bronchospams, should not be gien in patient with CHF, Risk of psychiatric disorder, not recomended with theophylline, patient with glastose intolerance should not use it, patient should reduce smoking, in case of clinically decrease weight lose treatment should be stoped.