Azilisartan Medoxomil (Azilisartan Medoxomil)
Overview of Azilisartan Medoxomil
Azilisartan Medoxomil is a prodrug and selective AT1 subtype Angiotensin II Receptor Antagonist.It is hydrolyzed to Azilisartan in GI tract. It blocks the binding of Angiotensin II to the AT1 receptor in vascular smooth muscle and adrenal gland and inhibits effect of Angiotensin.It is given for the treatment of hypertension
Indication of Azilisartan Medoxomil
Azilisartan Medoxomil is primarily indicated in conditions like Hypertension.
Contraindication of Azilisartan Medoxomil
Azilisartan Medoxomil is contraindicated in conditions like Pregnancy,Lactation.
Side Effects of Azilisartan Medoxomil
The symptomatic adverse reactions produced by Azilisartan Medoxomil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Nausea, Diarrhea, Cough, Asthenia, GI disorders, muscle spasm.
Precautions of Azilisartan Medoxomil
Discontinue drug in nursing. Avoid fetal and neonatal exposure.Monitor for worsening renal function in patients with renal artery stenosis.Correct volume salt depletion prior to its administration.Drink plenty of fluid while taking Azilisartan. Salt diet with Azilisartan can lead to dizziness and hypotension.Similarly the patients with diarrhea and vomitting are also at risk of developing dizziness and hypotension