Anagrelide (Anagrelide)
Overview of Anagrelide
Anagrelide is a drug which reduces blood platelet count. This mechanism is still under analysis that how it reduces the blood platelets. The research work on patients supports the hypothesis of dose-related reduction in platelet production followed a decrease in megakaryocyte hypermaturation.
Indication of Anagrelide
Anagrelide is primarily indicated in conditions like Chronic myeloid leukaemia, Thrombocythaemia, and can also be given in adjunctive therapy as an alternative drug of choice in Myeloproliferative disorders, Thrombosis.
Contraindication of Anagrelide
Anagrelide is contraindicated in conditions like Hypersensitivity.
Side Effects of Anagrelide
The signs and symptoms that are produced after the acute overdosage of Anagrelide include Peripheral edema.,The symptomatic adverse reactions produced by Anagrelide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Nausea, Vomiting, Anorexia, Diarrhea, Fever, Dyspnea, Palpitation, Tachycardia, Abdominal pain, Rashes, Pruritus, Pain, Pharyngitis, Dyspepsia, Malaise, Cough, Asthenia, Edema, Chest pain, Paresthesias, Back pain.
Precautions of Anagrelide
Anagrelide should be used with caution in patients with known or suspected heart disease, and only if the potential benefits of therapy outweigh the potential risks. The potential risks and benefits of anagrelide therapy in a patient with mild and moderate impairment of hepatic function should be assessed before treatment is commenced. There are no special requirements for dosing the geriatric population.