Dacarbazine (Dacarbazine)
Overview of Dacarbazine
Dacarbazine is an antineoplastic drug. Dacarbazine is a synthetic compound that functions as an alkylating agent. All alkylating agents have or can form an alkyl group that becomes covalently bound to cellular constituents. Dacarbazine is effective in the treatment of different cancers to slow or stop the growth of abnormal or cancerous cells. Dacarbazine is used in combination with different anticancerous drugs to obtain excellent therapeutic effects and to minimize unwanted effects or toxicities.
Indication of Dacarbazine
Dacarbazine is primarily indicated in conditions like Hodgkin's disease, Malignant melanoma, Metastatic melanoma, Metastatic melanoma, Metastatic melanoma, Metastatic melanoma, Neuroendocrine tumors, Soft tissue sarcoma.
Contraindication of Dacarbazine
No data regarding the contra indications of Dacarbazine is available.
Side Effects of Dacarbazine
The severe or irreversible adverse effects of Dacarbazine, which give rise to further complications include Photosensitivity.,Dacarbazine produces potentially life-threatening effects which include Hepatotoxicity, Moderate myelosuppression. which are responsible for the discontinuation of Dacarbazine therapy.,The signs and symptoms that are produced after the acute overdosage of Dacarbazine include Severe myelosuppression.,The symptomatic adverse reactions produced by Dacarbazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Alopecia, Diarrhea, Fever, Myalgia, Malaise, Facial flushing, Facial paresthesia, Alopecia.
Precautions of Dacarbazine
Dacarbazine should be used with caution in patients with pre-existing blood disorders, liver disease or kidney disease, dental disease. It is classified as pregnancy category C and not recommended for use in pregnancy or lactation.