Cyproheptadine Hcl (Cyproheptadine Hcl)
Overview of Cyproheptadine Hcl
Cyproheptadine is a serotonin and histamine antagonist with anticholinergic and sedative properties, resembles the phenothiazine antihistaminic agents in chemical structure and has potent H1 receptor blocking actions.
Indication of Cyproheptadine Hcl
Cyproheptadine Hcl is primarily indicated in conditions like Acromegaly, Advanced ovarian cancer, Angioedema, Anorexia nervosa, Antidepressant-induced inorgasmia, Appetite stimulation, Carcinoid syndrome, Cushing's syndrome, Hyperprolactinaemia, Migraine, Nelsons syndrome, NSAID associated ulceration, Pruritus, Symptomatic relief of allergy, To prevent recurrence of neural tube defect, Urticaria, Vascular headaches, and can also be given in adjunctive therapy as an alternative drug of choice in Severe nausea, vomiting (prevention).
Contraindication of Cyproheptadine Hcl
Cyproheptadine (HCl) is contraindicated in conditions like Asthma,Glucoma,Prostatism,Pyloric stenosis.
Side Effects of Cyproheptadine Hcl
The severe or irreversible adverse effects of Cyproheptadine (HCl), which give rise to further complications include Tachycardia, Hypotension, Psychiatric disturbances, Hypotension, Neurological disturbances, Palpitation, Urinary retention, Wheezing, Nasal blockage, GI upsets, Difficulties in micturition, Urinary retention.,Cyproheptadine (HCl) produces potentially life-threatening effects which include Blood dyscrasias, Hepatitis, Anaphylactic reactions. which are responsible for the discontinuation of Cyproheptadine (HCl) therapy.,The signs and symptoms that are produced after the acute overdosage of Cyproheptadine (HCl) include Flushing, Vomiting, Convulsions, Hallucinations, Dilated pupils, Ataxia, CNS depression.,The symptomatic adverse reactions produced by Cyproheptadine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Fatigue, Nausea, Dry mouth, Weight gain, Increased appetite, Dry mouth.
Precautions of Cyproheptadine Hcl
Cyproheptadine should be used with caution in bone marrow depression. Patients should observe caution while driving or performing other task requiring alertness because it may cause drowsiness. It should be used with caution in patients with urinary retention, history of bronchial asthma, hyperthyroidism, cardiovascular or liver disease. It should be used with caution in person with acute or chronic respiratory impairment, especially in children. Do not administer subcutaneously because irritation or lesion may occur.