Oxymetholone (Oxymetholone)
Overview of Oxymetholone
Oxymetholone, is a synthetic anabolic steroid used in the treatment of anemia and for the prophylaxis and treatment of hereditary angioedema.
Indication of Oxymetholone
Oxymetholone is primarily indicated in conditions like Anaemia, Aplastic anemia.
Contraindication of Oxymetholone
Oxymetholone is contraindicated in conditions like Hypercalcaemia,Breast cancer,Prostate cancer,Hepatic dysfunction,Hypersensitivity.
Side Effects of Oxymetholone
The severe or irreversible adverse effects of Oxymetholone, which give rise to further complications include Hepatitis, Insomnia, Liver cirrhosis.,The symptomatic adverse reactions produced by Oxymetholone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Nausea and vomiting, Acne, Bloating, Clitoral hypertrophy.
Precautions of Oxymetholone
Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne and clitoromegaly). To prevent irreversible change, drug therapy must be discontinued when mild virilism is first detected. Such virilization is usual following androgenic anabolic steroid use at high doses. Some virilizing changes in women are irreversible even after prompt discontinuance of therapy and are not prevented by concomitant use of estrogens. Menstrual irregularities, including amenorrhea, may also occur. The insulin or oral hypoglycemic dosage may need adjustment in diabetic patients who receive anabolic steroids. Concurrent dosing of an anabolic steroid and warfarin may result in unexpectedly large increases in the INR or prothrombin time (PT). When an anabolic steroid is prescribed to a patient being treated with warfarin, doses of warfarin may need to be decreased significantly to maintain the desirable INR level and diminish the risk of potentially serious bleeding.