Methocarbamol (Methocarbamol)
Overview of Methocarbamol
Methocarbamol is a central muscle relaxant for skeletal muscles, used to treat spasms. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perhaps by general depressant effects. It has no direct relaxant effects on striated muscle, nerve fibers, or the motor endplate. It will not directly relax contracted skeletal muscles. The drug has a secondary sedative effect.
Indication of Methocarbamol
Methocarbamol is primarily indicated in conditions like Painful musculoskeletal conditions.
Contraindication of Methocarbamol
Methocarbamol is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects of Methocarbamol
The signs and symptoms that are produced after the acute overdosage of Methocarbamol include Hypotension, Coma, Seizures, Blurred vision, Leucopenia.,The symptomatic adverse reactions produced by Methocarbamol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Headache, Drowsiness, Fever, Blurred vision, Bradycardia, Jaundice, Dyspepsia, Flushing, Tremor, Hypersensitivity, Nausea and vomiting, Edema, Convulsions, Angioedema, dyspepsia.
Precautions of Methocarbamol
Methocarbamol may inhibit the effect of pyridostigmine bromide. Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents. Methocarbamol may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to engage in such activities. Since methocarbamol may possess a general CNS depressant effect, patients receiving ROBAXIN Injectable should be cautioned about combined effects with alcohol and other CNS depressants.