Ioxaglate (Ioxaglate)
Overview of Ioxaglate
Ioxaglate is an iodinated, water soluble, ionic, monoacidic dimeric contrast medium. It is a diagnostic radiopaque medium used in angiography, aortography, urography.
Indication of Ioxaglate
Ioxaglate is primarily indicated in conditions like Angiography, Arthrography, Urography, and can also be given in adjunctive therapy as an alternative drug of choice in Hysterosalpingography.
Contraindication of Ioxaglate
Ioxaglate is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects of Ioxaglate
The severe or irreversible adverse effects of Ioxaglate, which give rise to further complications include Myocardial infarction.,The signs and symptoms that are produced after the acute overdosage of Ioxaglate include Seizures, Thromboembolism, Hypersensitivity reactions.,The symptomatic adverse reactions produced by Ioxaglate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fever, Anxiety, Sweating, Chills, Rashes, Nausea and vomiting, Chest pain, dizziness.
Precautions of Ioxaglate
Diagnostic procedures which involve the use of iodinated intravascular contrast agents should be carried out under the direction of personnel skilled and experienced in the particular procedure to be performed. All procedures utilizing contrast media carry a definite risk of producing adverse reactions. While most reactions are minor, life-threatening and fatal reactions may occur without warning, and this risk must be weighed against the benefit of the procedure. Acute renal failure has been reported in diabetic patients with diabetic nephropathy and in susceptible nondiabetic patients (often elderly with pre-existing renal disease) following the administration of iodinated contrast agents. Therefore, careful consideration of the potential risks should be given before performing this radiographic procedure in these patients.Ioxaglate salts are excreted unchanged in human milk. Because of the potential for adverse effects in nursing infants, bottle feedings should be substituted for breast feedings for 24 hours following the administration of this drug.