Ziprasidone (Ziprasidone)
Overview of Ziprasidone
Ziprasidone is a new antipsycotic drug with combined dopamine and serotinin receptor antagonist activity.
Indication of Ziprasidone
Ziprasidone is primarily indicated in conditions like Schizophrenia, and can also be given in adjunctive therapy as an alternative drug of choice in Depression, Mania, Tourette's syndrome.
Contraindication of Ziprasidone
Contraindications
Side Effects of Ziprasidone
The severe or irreversible adverse effects of Ziprasidone, which give rise to further complications include Rashes, Fever, Muscle twitching, QT prolongation.,Ziprasidone produces potentially life-threatening effects which include Seizures. which are responsible for the discontinuation of Ziprasidone therapy.,The signs and symptoms that are produced after the acute overdosage of Ziprasidone include Constipation, Dyspepsia, Sedation, Somnolence.,The symptomatic adverse reactions produced by Ziprasidone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Anxiety, Confusion, Somnolence, Sneezing, Sexual dysfunction, Obesity, Agitation, Blood dyscrasias, Cholestatic Jaundice, Orthostatic hypotension, Hypertension, Hyperlipidemia, GI disturbance, Hepatitis, Hyperglycemia, Hyperprolactinemia, Tardive dyskinesia, Extra pyramidal symptoms, Seizures.
Precautions of Ziprasidone
Ziprasidone should be avoided in combination with other drugs that are known to prolong QTc interval.Avoid use of alcohol.Avoid activities involving high temperature. It should not be used in patients with a history of seizures and cerebrovascular disease.