Floxuridine (Floxuridine)
Overview of Floxuridine
Floxuridine is an oncology drug that belongs to class known as "antimetabolites". It's an antineoplastic which acts as an antimetabolite, either by convession to Flourouracil which produces greater inhibition of DNA synthesis
Indication of Floxuridine
Floxuridine is primarily indicated in conditions like Colorectal cancer, Gastrointestinal stromal tumour, Neoplasms.
Contraindication of Floxuridine
Floxuridine is contraindicated in conditions like Infections,Myelosuppression,Nutrition deficiency.
Side Effects of Floxuridine
The severe or irreversible adverse effects of Floxuridine, which give rise to further complications include Allergic reactions, Bleeding, Fatigue.,Floxuridine produces potentially life-threatening effects which include Cirrhosis of the liver. which are responsible for the discontinuation of Floxuridine therapy.,The signs and symptoms that are produced after the acute overdosage of Floxuridine include Nausea, Vomiting, Diarrhea, GI ulceration, Bone marrow depression.,The symptomatic adverse reactions produced by Floxuridine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Rashes, Stomatitis, Erythema, Itching, Nausea and vomiting, stomach cramping, Stomach cramping, Myocardial Ischemia.
Precautions of Floxuridine
Floxuridine should not be given to allergic patients. Floxuridine should be given only under the supervision of qualified doctor experienced in cancer chemotherapy. Due to severe toxic effects all patients should be hospitalized for initial course of therapy. aoid contact with people having cold,fluor any contageous illness and also who have been vaccinated with live vaccine recently. Should be used with caution in impaired Kidney & renal function