Quinestrol (Quinestrol)
Overview of Quinestrol
Quinestrol is synthetic origin used in hormone replacement therapy and occassionally to treat breast cancer and prostate cancer.
Indication of Quinestrol
Quinestrol is primarily indicated in conditions like Hormone replacement therapy, Menopausal flushing, and can also be given in adjunctive therapy as an alternative drug of choice in Breast cancer, Prostate cancer.
Contraindication of Quinestrol
Quinestrol is contraindicated in conditions like Vaginal bleeding,Porphyria,Pregnancy.
Side Effects of Quinestrol
The severe or irreversible adverse effects of Quinestrol, which give rise to further complications include Systemic lupus erythematosus.,Quinestrol produces potentially life-threatening effects which include Venous thromboembolism. which are responsible for the discontinuation of Quinestrol therapy.,The signs and symptoms that are produced after the acute overdosage of Quinestrol include Shortness of breadth, Vaginal bleeding.,The symptomatic adverse reactions produced by Quinestrol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Weight gain, Nausea and vomiting, Fluid retention, Bloated feeling.
Precautions of Quinestrol
It should not be given to the patients with active thrombophlebitis or thromboembolic disease, abnormal vaginal bleeding, women with antiphospholipid antibodies, history of endometriosis. when used as HRT, it should be used with caution in diseases which may be excerbated during pregnancy or quinestrol therapy including diabetes, asthma, epilepsy, hypertension, cardiac or renal disease, sickle cell anemia, multiple sclerosis and cholera. It should not be used during lactation.