Nitroprusside (Nitroprusside)
Overview of Nitroprusside
NITROPRUSSIDE is a vasodilator that relaxes blood vessels. It reduces blood pressure, increases the blood and oxygen supply to the heart, and decreases the workload on the heart. Nitroprusside helps to reduce blood pressure in a hypertensive (high blood pressure) emergency, and helps to lower the blood pressure during surgery to prevent excessive bleeding. Nitroprusside is not for long-term use. Generic nitroprusside injections are available.
Indication of Nitroprusside
Nitroprusside is primarily indicated in conditions like Congestive heart failure, Hypertension, Hypertensive crisis, and can also be given in adjunctive therapy as an alternative drug of choice in Pre-eclampsia.
Contraindication of Nitroprusside
Nitroprusside is contraindicated in conditions like Renal failure.
Side Effects of Nitroprusside
Nitroprusside produces potentially life-threatening effects which include Tachycardia. which are responsible for the discontinuation of Nitroprusside therapy.,The signs and symptoms that are produced after the acute overdosage of Nitroprusside include Cyanide toxicity.,The symptomatic adverse reactions produced by Nitroprusside are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Sweating, Confusion, Pain, Redness, Hypotension, Flushing, Confusion, dizziness, Palpitations, Hypotension.
Precautions of Nitroprusside
Blood pressure should be frequently monitored and recorded. Should be use with caution in patients with renal function. Because of its rapid onset, efficacy and short duration of action, nitroprusside should be administerd by infusiob pump and arterial blood pressure should be continuosly monitored via intra arterial recording. It Should be used with caution in hepatic impairment