Estramustine (Estramustine)
Overview of Estramustine
Estramustine is a cancer (antineoplastic) medication. Estramustine interferes with the growth and spread in the body. Estramustine used to treat prostate cancer.
Indication of Estramustine
Estramustine is primarily indicated in conditions like Palliative surgery., Prostate cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Metastatic, Prostatic cancer.
Contraindication of Estramustine
Estramustine is contraindicated in conditions like Thrombophlebitis,Thrombo-embolic complications,Hypersensitivity to any component of product.
Side Effects of Estramustine
The severe or irreversible adverse effects of Estramustine, which give rise to further complications include Thrombocytopenia, Confusion, Chest pain, Hepatic dysfunction.,Estramustine produces potentially life-threatening effects which include Hypertension, Thromboembolism, Leukopenia. which are responsible for the discontinuation of Estramustine therapy.,The signs and symptoms that are produced after the acute overdosage of Estramustine include Nausea, Vomiting, Mylosuppresion.,The symptomatic adverse reactions produced by Estramustine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Nausea, Rashes, Itching, Loss of libido, Loss of appetite.
Precautions of Estramustine
Should be used with caution in patients with the history of thrombophlebitis, thrombosis, thromboembolicn disorders. Because hypertension may occur bloodpressure should be monitored periodically. Patients with prostate cancer and osteoblastic metastases are at risk for hypocalcemia and should have calcium levels closely monitored.