Atazanavir (Atazanavir)
Overview of Atazanavir
Atazanavir is an antiviral agent, active against HIV infection. It belongs to protease inhibitors. Atazanavir is used in combination with other antiretroviral drugs in patients previously treated with antiretroviral.
Indication of Atazanavir
Atazanavir is primarily indicated in conditions like HIV infection in combination with other antiretroviral drugs.
Contraindication of Atazanavir
Atazanavir is contraindicated in conditions like Diabetes mellitus,Hypersensitivity.
Side Effects of Atazanavir
The symptomatic adverse reactions produced by Atazanavir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Alopecia, Diarrhea, Anxiety, Dyspnea, Palpitation, Jaundice, Mouth ulcers, Depression, Arthralgia, Peripheral neuropathy, Syncope, Increased appetite, Chest pain, Urinary frequency, Hypertension, Nephrolithiasis, Amnesia, Proteinuria, Abnormal dreams, Weight changes.
Precautions of Atazanavir
Concomitant use with drugs that prolong PR interval; cardiac conduction disorders. Protease inhibitors are associated with hyperglycaemia and should be used with caution in diabetes. Caution is also needed in patients with haemophilia who may be at increased risk of bleeding. Protease inhibitors should be used with caution in hepatic impairment; the risk of hepatic side-effects is increased in patients with chronuc hepatitis B or C. Atazanavir and fosamprenavir may be used at usual doses in patients with renal impairment. Protease inhibitors should also be used with caution in pregnancy.